Evaluation of the analgesic effect of Thymus kotschyanus hydroalcoholic extract in male mice by formalin and tail flick tests

نویسندگان

  • Akram Allahverdi Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Azam Bakhtiarian* Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Muhammad Imran Khan Department of Pharmacology, School of Medicine, International Campus, Tehran University of Medical Sciences, Tehran, Iran.
  • Sattar Ostadhadi Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Vahid Nikoui Razi Institute for Drug Research, Iran University of Medical Sciences, Tehran, Iran
چکیده مقاله:

Background and Objective: Considering the wide side effects of synthetic pain killers, use of herbal drugs in folk medicine as analgesic agents has increased. In the present work, we tried to uncover the pharmacological potential of ethanolic extracts by using various animal models and also to explore the potent antinociceptive effect of the plant Thymus kotschyanus. Materials and Methods: The ethanolic extract from the aerial part of Thymus kotschyanus after intraperitoneal administration at doses of 50, 100 and 200 mg/kg was evaluated against pain using formalin test and tail flick test. Results: Thymus kotschyanus extract at doses of 100 mg/kg (p

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evaluation of the analgesic effect of thymus kotschyanus hydroalcoholic extract in male mice by formalin and tail flick tests

background and objective: considering the wide side effects of synthetic pain killers, use of herbal drugs in folk medicine as analgesic agents has increased. in the present work, we tried to uncover the pharmacological potential of ethanolic extracts by using various animal models and also to explore the potent antinociceptive effect of the plant thymus kotschyanus. materials and methods: the ...

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عنوان ژورنال

دوره 4  شماره 1

صفحات  1- 6

تاریخ انتشار 2016-03-01

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